In Vitro and in Vivo Evaluation of Sustained Release Chitosan-Coated Ketoprofen Microparticles
نویسندگان
چکیده
منابع مشابه
In vitro and in vivo evaluation of sustained release chitosan-coated ketoprofen microparticles.
Simple ketoprofen microspheres (MS) were prepared by the dry-in-oil method using ethylcellulose (EC) as a matrix polymer. Further, the microspheres modified by addition of polyethylene glycol (PEG) and hydroxypropyl cellulose (HPC), called MS-P and MS-H, respectively, were prepared. The in vitro release from MS, MS-P and MS-H was examined in the JP XIII second fluid, pH 6.8, at 37 degrees C and...
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In this study, an attempt was made to deliver pantoprazole in a sustained manner using delayed release tablets. The tablets were prepared by the wet granulation method using HPMC, cassava starch and polyvinyl pyrrolidine as polymers, Avicel PH 102 (MCC) as filler and potato starch as binder. The prepared tablets were evaluated for hardness, mass variation, friability and drug content uniformity...
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متن کاملIn-vitro study of Ketoprofen release from synthesized silica aerogels (as drug carriers) and evaluation of mathematical kinetic release models
Silica aerogels are porous and extremely lightweight nano-materials shows interesting properties. These materials, because of biocompatibility, non-harmful to the body and special physical characteristics such as large surface area and low density have great potential for use in a drug delivery system (DDS). The focus of this study is the evaluation of the effects of silica aerogels on improvin...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 2001
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi.121.239